The Research Regulatory Oversight Office (R2O2) is responsible for oversight of intramural and extramural research activities involving humans and animals to ensure compliance with all legal and ethical requirements. Our oversight responsibility includes FDA regulated studies, research and testing with animals, and implementation of the research integrity and misconduct rules. The scope of our oversight includes all institutions under the purview of the Under Secretary of Defense for Personnel and Readiness and clinical investigations conducted in the Military Health System.
Human Research Protection Program (HRPP) Intramural is the OUSD(P&R) component oversight office for 32 CFR 219 – “Protection of Human Subjects” and DoDD 3216.02, “Protection of Human Subjects and Adherence to Ethical Standards in DoD-Sponsored Research”. R2O2 manages a review and oversight process for research conducted by OUSD(P&R) employees or institutions, including policy implementation, and training of researchers and reviewers.
Human Research Protection Program (HRPP) Extramural is the OUSD(P&R) component oversight office for 48CFR 207, 235, 252 Defense Federal Acquisition Regulation, “Protection of Human Subjects in Research Projects”. R2O2 manages the Human Research Protection Official (HRPO) review and oversight process for research sponsored by OUSD(P&R) institutions through grants or contracts.
Animal Care and Use in Research and Testing Program is the P&R component level oversight office for the authorities and responsibilities under 9 CFR 2, 7 USC 2131-2156, “Animal Welfare Act” and DoDI 3216.01, “Use of Animals in DoD Programs”. R2O2 manages the Animal Care and Use review and oversight process for research conducted and supported by OUSD(P&R) institutions.
Research Integrity and Misconduct Program is the P&R component level oversight office for the authorities and responsibilities under DoDI 3210.7 implementing the “Federal Policy on Research Misconduct”. R2O2 manages an adjudication process for research misconduct, including falsification, fabrication, and plagiarism.